The film is dedicated to the 250th anniversary of the founding of the Academy of Sciences. Based on archival film documents, photographs and filming of manuscripts, books and portals to full members of the Academy of Sciences, the film tells about the role of the Academy in the development of science and economics, about outstanding figures of the Academy. The research vessel "Yuri Gagarin" is on the way. View of the Earth from space. Nuclear reactor of the Voronezh nuclear power plant. Archaeological excavations in Novgorod. Academician B. A. Rybakov talks about the importance of historical science (synchronously). Birch bark letters. The building of the St. Petersburg Academy of Sciences. Decree of Peter I. Sculpture of Peter I. Portraits of full members of the St. Petersburg Academy of Sciences M. V. Lomonosov, P. L. Chebyshev, B. S. Jacobi, A. M. Butlerov, I. M. Sechenov, K. M. Baer, D.I. Mendeleev. Monument to MV Lomonosov in front of the building of Moscow State University. An office in the building of the Academy of Sciences; a plate on the table with the inscription: "M. V. Lomonosov sat here." Former laboratory of M.V. Lomonosov. Old books. Portraits of foreign members of the Academy of Sciences J. Delambert (France), C. Linnaeus (Sweden), R. Reomuca (France). Book of N.I. Lobachevsky. Manuscripts, portrait of N.I. Lobachevsky. Portraits of P. S. Pallas, S. G. Gmelin. Portrait of N. Ye. Zhukovsky. Photo by V. I. Vavilov. V. I. Lenin in the Kremlin during a conversation with the American journalist L. Eyre in February 1920. Articles, photograph by K. A. Timiryazev. Film portraits of the first president of the USSR Academy of Sciences A. N. Karpinsky, academicians N. S. Kurnakov, V. I. Vernadsky, S. A. Chaplygin, A. F. Ioffe, N. N. Semenov. NN Semenov's story about the creation of research institutes (synchronously). Academician A. N. Bach in the laboratory. K. E. Tsiolkovsky at work; model of the airship. Academician I. P. Pavlov with colleagues. Photo of Academician V.A.Obruchev. Film portraits of A. E. Fersman, P. P. Lazarev. L. A. Kulik's expedition to the area of the fall of the Tunguska meteorite. A ceremonial meeting dedicated to the CEC resolution on assigning the name of the USSR Academy of Sciences to the Russian Academy; MI Kalinin speaks. Construction of the Volkhovskaya hydroelectric power station, development of the Kuznetsk coal basin. Students in classrooms and laboratories of institutes. Academician E.O. Paton in the office. Academician A. P. Karpinsky at the plant. A cyclotron manufactured at the Electrosila plant in Leningrad. Meeting of the Academy of Sciences; present A. P. Karpinsky, G. M. Krzhizhanovsky, A. V. Lunacharsky, D. N. Pryanishnikov. Construction of the Magnitogorsk Metallurgical Combine. Academician D. V. Nalivkin at work. Chairman of the Kyrgyz branch of the USSR Academy of Sciences K. L. Skryabin in the car. Academician O. Yu. Schmidt and members of his expedition. Academician S. I. Vavilov in the laboratory. Film portraits of academicians P. A. Cherenkov, P. L. Kapitsa, I. V. Kurchatov, G. N. Flerov. Meeting of the VI Mendeleev Congress in November 1932, Academician I. M. Gubkin speaks (synchronously). Meeting of the Academy of Sciences in 1934. Presentation of a diploma to Academician A. N. Krylov. A ceremonial meeting dedicated to the 200th anniversary of the Academy of Sciences. Academician I. P. Bardin, minister I. T. Tevosyan and secretary of the regional committee L. I. Brezhnev at the Zaporizhstal metallurgical plant. Academicians I. G. Petrovsky and A. N. Kolmogorov. The building of the USSR Academy of Sciences in Moscow. Meeting of the Academy of Sciences; President of the USSR Academy of Sciences AN Nesmeyanov speaks. Academician IV Kurchatov talks about the use of atomic energy (synchronously). Nuclear icebreaker "Lenin" on the way. View of the Novosibirsk Academgorodok. Interview with Academician M. A. Lavrentyev (synchronously), A. V. Sadykov (synchronously), P. N. Fedoseev (synchronously), Yu. A. Ovchinnikov (synchronously). Students in the classrooms of Tashkent University. The building of the Academy of Sciences of the Ukrainian SSR. President of the Academy of Sciences of the Latvian SSR Malmeister with colleagues. President of the Academy of Sciences of the USSR M. V. Keldysh in the office. Film portraits of academicians A.M. Prokhorov, A.P. Alexandrov, N.G. Basov, A.P. Vinogradov, V.A.Kotelnikov. Academician P.P. Lukyanenko in the laboratory. Wheat samples. Biological scientists in the laboratory. Academician A. V. Sidorenko talks about gas fields (synchronously). Computing center. Academician V. A. Kirillin with colleagues. American scientists visit the Institute of Chemical Physics. President of the Academy of Sciences of the USSR M.V. Keldysh in the physics laboratory of Great Britain. French professor Y. Kurien talks about cooperation with Soviet scientists (synchronously). UNESCO building in Paris. Building of the Joint Institute for Nuclear Research. Interview with academicians L. D. Landau, I. E. Tamm, N. N. Bogolyubov, A. P. Vinogradov (synchronously). Academician N. G. Basov in the laboratory; the laser installation works. Observatory. Interview with Academician V. A. Ambartsumyan (synchronously). Academician S. P. Korolev rises in the elevator. Space rocket launch. Eruption.